Abstract

Advanced retinal pigment epithelium analysis by SD-OCT to monitor dry AMD progression

Author(s): Albert J Augustin

This article provides a short overview of developments in optical coherence tomography (OCT) technology and highlights the advantages of spectral domain OCT, which allows for high-speed, high-resolution imaging of retinal structures. Established clinical applications to diagnose and monitor macular diseases are summarized and the rapidly evolving role of OCT technology in this field is described. Recent clinical studies show that spectral domain OCT permits volumetric measurement of drusen and might be used for quantitative assessment of drusen progression. Furthermore, spectral domain OCT fundus images can be used to evaluate atrophic lesions of geographic atrophy. A new retinal pigment epithelium analysis tool is presented that should allow for automated, quantitative assessment of drusen and atrophic lesions and could potentially provide more objective and easier classification of age-related macular degeneration.