Abstract

Advances in the Diagnosis and Treatment of Systemic Lupus Erythematosus (SLE)

Author(s): Mia Turner*

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect multiple organs, leading to significant morbidity and mortality. Despite being recognized for centuries, the complexity of its pathogenesis, heterogeneous clinical presentation, and fluctuating disease course pose substantial challenges in its diagnosis and management. Advances in the understanding of SLE's immunologic mechanisms, the identification of novel biomarkers, and the development of targeted therapies have significantly altered the treatment landscape. This article reviews the current diagnostic criteria, emerging biomarkers, and new treatments for SLE, with an emphasis on biologic therapies such as belimumab, anifrolumab, and other promising interventions. We also discuss the impact of personalized medicine and precision healthcare in optimizing patient care. While these advancements hold promise for improved clinical outcomes, further research is essential to address gaps in early diagnosis, effective disease monitoring, and long-term management strategies.