Abstract

Association between arterial stiffness and bone mineral density

Author(s): Yoshiko Mizuno*

Cardiovascular Disease (CVD) and osteoporosis are major public health problems that share common pathophysiological mechanisms besides aging. Although a global increase in life expectancy is a huge achievement driven by improvements in public health care, many societies across the world are not prepared for an aging society. Especially in elderly people, so-called multimorbidity, prevalence of which ranges from 55%-98% worldwide, is a problematic issue that needs to be solved. For this reason, acting on aging biology itself rather than modifying a single disease-specific process is highly recommended. In a recent study, we examined the relationship between Bone Mineral Density (BMD) and multiple cardiovascular measurements in Japanese general population without overt CVD and has demonstrated the partial relationship of osteoporotic state and enhanced arterial stiffness, as evaluated by Cardio-Ankle Vascular Index (CAVI). Keywords: Arterial stiffne