Abstract

Commentary on Pyrrole-Imidazole Alkaloids.

Author(s): Mohamad Taleuzzaman

Synthesize marine sponge-deriving pyrrole-imidazole alkaloids. This now nearly triple- digit membered community has been growing exponentially in the last 20 years, both in terms of new representatives and topological complexity − from simple, achiral oroidine to the breathtaking 12-ring stylissadines A and B, each possessing 16 stereocenters. This review will account for the progress in achieving the total synthesis of the more biologically enticing members of this class of natural products


PDF