Abstract

Insulin aspart for the treatment of Type 2 diabetes

Author(s): V Seshiah, Sanjay Kalra, Vijayam Balaji & Madhuri Balaji

Insulin aspart is a rapid-acting insulin analog and is approved for use in Type 1, Type 2 and gestational diabetes. Following the subcutaneous injection, it more closely mimics the physiological release of insulin in the human body with a faster onset and shorter duration of action. It also offers several advantages like flexibility in mealtime administration, better glycemic control in the form of superior control of postprandial glucose excursion and less nocturnal hypoglycemia as compared with regular human insulin. It is safe to use in patients with renal and hepatic impairment and is approved for use in pregnancy, in children above 2 years of age, in continuous subcutaneous infusion pumps and can be used intravenously in hospital settings.