Abstract

Measurement properties of patient-reported outcome measures of medication adherence in cardiovascular diseases: Protocol for systematic review

Author(s): Roberta Cunha Matheus Rodrigues

Statement of the Problem: Cardiovascular diseases are among the main causes of death worldwide and pharmacological treatments greatly reduce the risk of cardiovascular events; however, a large number of patients do not adhere to treatment. There are many self-reported measures available in the literature to assess medication adherence among patients with cardiovascular diseases. Nonetheless, systematic reviews assessing the psychometric performance of self-reported measures of medication adherence among these patients were not found. The aim of this study is to critically assess, compare and synthesize the quality of the measurement properties of patientreported outcome measures for assessment of medication adherence among patients with cardiovascular diseases. Methodology & Theoretical Orientation: This protocol was developed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) following the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidelines for the review of patient-reported outcome measures. The following databases will be searched: Web of Science, SCOPUS, MEDLINE/PubMed, CINAHL, Embase, LILACS and PsycINFO. OpenGray, ProQuest and Google Scholar will be used to search the gray literature. Conclusion & Significance: This systematic review protocol will broaden understanding of the methodological rigor and reliability of this proposed review in addition to deepening knowledge on the assessment of psychometric properties of self-reported measures assessing medication adherence in the context of cardiovascular diseases. This review’s results will support the recommendation of an instrument presenting the best psychometric evidence to measure medication adherence among patients