Abstract

New Treatments for Newborn Seizures

Author(s): Peter Cox

The treatments for neonatal seizures, a frequent neurologic emergency, have not altered appreciably in decades. Acute symptomatic seizures and epilepsies with neonatal beginnings are unique from other types of seizures, and advances in diagnostic and pathophysiologic knowledge of these traits give extraordinary opportunities for the development of precision therapeutics with the potential to enhance outcomes. Here, we go over the biology of newborn seizures and a discussion of the research supporting the various treatments that are currently in use. We discuss cutting-edge treatments for the management of acute symptomatic newborn seizures that are now undergoing clinical and preclinical testing. Finally, we explore the function of precision medicines for hereditary neonatal-onset epilepsies and discuss challenges and objectives for creating novel clinical therapies.