Abstract

The Pathophysiology Concept of Stress Ground State Drift and Its General Clinical Significance (Revealing the Modern Medical Laws Implied in the Core Theories of Traditional Chinese Medicine)

Author(s): Xiaolin Zhao

This article defines the phenomenon that the Neuroendocrine Trunk (NET) activity (index) in the basic state continuously deviates from the median value within the normal range and is accompanied by corresponding characteristic manifestations as the Stress Ground State Drift (SGSD) (grade I), which is classified and graded according to causes, symptoms and indicators, and explains its formation mechanism, adding new content to the framework of classical stress theory, and proposing the diagnosis and intervention principles. The SGSD concept summarizes and explains the important essence of the concept categories of the core theories of Traditional Chinese Medicine (TCM), such as Kidney, SourceQi, Yin-Yang, and the differentiation of Cold-Heat, Deficiency-Excess of Internal- Syndromes, and its relevance to the regulatory systems, such as Stress-Related Neuroendocrine Trunk (SRNET), thyroid and gonadal axes (HPT and HPG), and pathophysiology of Modern Medicine (MM), and then generally associated with many diseases, especially refractory diseases. In an effort to reveal the common pathological mechanism of MM "endogenous" diseases implied in the core theory of TCM, and the key scientific laws of its diagnosis and intervention, which should have important guiding significance for widely and effectively improving the efficacy of MM diseases. SGSD also has multiple important meanings as a link for the systematic “fusion” of TCM core theories into MM.