Abstract

To study Antimitotic Activity of Momordica Dioica Fruits on Allium Cepa Root Meristamatic cells

Author(s): Rajesh A. Ahirrao

Objective: Various parts of Momordica dioica commonly known asspiny gourdused for treatments of various diseases in today’s world. Natural occurring phenolic compounds play an important role in cancer prevention and shows antimitotic activity. Number of active constituents like phenolic acid, curcuminoids, coumarine, ligans, quinones, etc. is showing antimitotic activity of Momordica dioica. The present work is on phytochemical investigation and examines antimitotic activity of aqueous extract of fruits Momordica dioicaon Allium cepa root meristamatic cells.
Methods: The fruits are air dried and extracted with solvents like water by maceration method. The evaluation of antimitotic activity is done by using Allium cepa root meristamatic cells parameters where and methotrexate was used as a standard drugs.