Stem Cell Research and Regenerative Medicine

Bone Marrow Transplantation

A bone marrow transplant is a process for replacing damaged or destructed bone marrow with healthy stem cells of the bone marrow. Bone marrow is the tissue within the bones which is soft and fat. The blood cells are produced by bone marrow. Stem cells in the bone marrow are immature cells which give rise to all of your different blood cells. It can be administered chemotherapy, radiation, or both before transplantation. This can take two forms: Ablative (myeloablative) medication — High-dose chemotherapy, radiation, or both are administered to kill all cells. This also destroys all remaining healthy bone marrow, which enables the development of new stem cells in the bone marrow. Reduced intensity treatment, also called a mini transplant — Before a transplant, lower doses of chemotherapy and radiation are given. This allows for transplantation of elderly people, and those with other health issues. 

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