ISSN: 2041-6792

Clinical Investigation

Cirrhosis

 Cirrhosis is an outcome of the constant liver injury, fibrosis, inflammation and necrosis. Alcoholism and chronic hepatitis B and C are commonly known to cause cirrhosis. The fibrosis existing in cirrhosis occurs from the secretion of TGF-beta cells. The end stage of the liver disease usually represents Cirrhosis, in such case the liver function is greatly negotiated. The lessened ability of the production of protein and detoxified substances results in signs of hyperestrinism, portal hypertension and hypoalbuminemia. Diminished coagulation factor synthesis results in coagulopathy and its performance rises from the indices of contracted hepatic function and portal high blood pressure.  

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