Journal of Biochemistry Research

Gastrografin

 Gastrografin are often given by enema for non-operative treatment of uncomplicated meconium ileus. Advantage is taken of the high pressure of the contrast medium: the encompassing tissue is forced to release considerable amounts of fluid, which then flows into the gut and dissolves the inspissated meconium.   The procedure must be administered slowly and only under fluoroscopic control. Injection should stop as soon as Gastrografin is seen to enter the ileum. due to its high osmolarity, Gastrografin may cause the loss of an outsized amount of fluid into the intestines. An drip must therefore be found out before the enema is given and fluid should be infused as needed . If the Gastrografin isn't expelled during the primary hour after removal of the rectal catheter, an X-ray should be taken to make sure that overdistension of the bowel as a results of the high osmolarity of Gastrografin has not occurred.  

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