Spinal Disorders Open Access Journals
Spinal disorders thanks to trauma, pathology, or normal
aging can compromise the standard of life. The structure and performance of the spine are unique and really complex. The intervertebral disk (IVD) plays a crucial role within the
biomechanics of the spine since its mechanical function leads to absorbing shock and distributing axial loads whilst providing flexibility. For this reason, the IVD degeneration could also be considered one among the foremost common causes of low back pain. Indeed, the progressive degeneration usually provides a loss of water and a consequent loss of disc height. Thus the annulus fibrous and ligaments result pretensioned, creating a mechanically unstable
environment which can cause a spinal degenerative cascade. Albeit good short-term clinical results are obtained through fusion for traumatic and degenerative spinal disorders, long-term studies have shown an alteration within the spine stability. So as to beat these problems, a man-made IVD has been proposed as an alternate to fusion. Consequently, several models of IVD prosthesis are developed to revive the traditional kinematics and load-sharing properties of the natural IVD. Over the past years, metals, ceramics, and
polymers are widely involved in designing interbody fusion devices and IVD prostheses. Due to their ability to mimic the structure and therefore the mechanical properties of natural tissues, polymer-based composite
biomaterials are developed to beat the drawbacks associated with the utilization of conventional materials.
High Impact List of Articles
-
Achieving scarless renal surgery: is it feasible?
Li June Tay, Marios Hadjipavlou, Shahid Khan and Abhay Rane
Review Article: Clinical Practice
-
Achieving scarless renal surgery: is it feasible?
Li June Tay, Marios Hadjipavlou, Shahid Khan and Abhay Rane
Review Article: Clinical Practice
-
Unusual small bowel metastatic localization in a castration-resistant prostate cancer patient
Francesca Maines, Orazio Caffo, Antonello Veccia and Enzo Galligioni
Case Report: Clinical Practice
-
Unusual small bowel metastatic localization in a castration-resistant prostate cancer patient
Francesca Maines, Orazio Caffo, Antonello Veccia and Enzo Galligioni
Case Report: Clinical Practice
-
Castrate-resistant prostate cancer: the right targets and combinations
Joyson Karakunnel and William Dahut
Review Article: Clinical Practice
-
Castrate-resistant prostate cancer: the right targets and combinations
Joyson Karakunnel and William Dahut
Review Article: Clinical Practice
-
Idursulfase for enzyme-replacement therapy in mucopolysaccharidosis II
J Edmond Wraith
Drug Evaluation: Clinical Practice
-
Idursulfase for enzyme-replacement therapy in mucopolysaccharidosis II
J Edmond Wraith
Drug Evaluation: Clinical Practice
-
Dalteparin sodium in the management of thromboembolic disorders
Agnes YY Lee
Drug Evaluation: Clinical Practice
-
Dalteparin sodium in the management of thromboembolic disorders
Agnes YY Lee
Drug Evaluation: Clinical Practice
-
Role of immunologic and inflammatory factors in the development of endometriosis: indications for treatment strategies
Attila Mihalyi, Kyama C Mutinda, Peter Simsa, Sophie Debrock, Jason M Mwenda and Thomas M D\'Hooghe
Review Article: Clinical Practice
-
Role of immunologic and inflammatory factors in the development of endometriosis: indications for treatment strategies
Attila Mihalyi, Kyama C Mutinda, Peter Simsa, Sophie Debrock, Jason M Mwenda and Thomas M D\'Hooghe
Review Article: Clinical Practice
Relevant Topics in Clinical